Study of Event-related Potential in Patients with Acute Stroke
TAO Ding-bo SUN Xiu-lan SUN Xiao-pei
(First Affiliated Hospital, Dalian Medical University,Dalian 116021,China)
【Abstract】 Objective: To study P3 wave features of event-related potential in patients with acute stroke. Methods: P3 was elicited from Cz by auditory “oddball paradigm”. The peak latency and amplitude were measured in 30 patients and 41 controls. Results: There was significant increase in P3 latency (P<0.05) and decrease in P3 amplitude (p<0.05) in patients with acute stroke. Conclusion: The results reflected possible cognitive impairments in patients with acute stroke.
【Key words】 Acute stroke; Event-retated potential; Cognitive function
脑血管病是神经科最常见的疾病之一,在我国其死亡率及致残率居城市人口的前列[1],故对脑血管病的防治研究日趋紧迫。以往对脑血管病的研究多集中在病理、生化、影像学等方面,而运用事件相关电位技术研究较少。近几年,我们对30名急性期脑卒中患者作了事件相关电位测查,报告如下。
1 对象和方法
1.1 研究对象
患者30名,其中男20名,女10名,年龄38~78岁,平均年龄58岁,脑梗塞20名,脑出血18名,病变部位均为一侧基底节区。检查均在发病20天以内进行。
对照组41名,均为正常人或无神经精神疾病的门诊病人,其中男19名,女22名,年龄40~60岁,平均58岁。
1.2 检查方法
1.3 判断异常标准