微波急性辐照对兔组织生物力学特性的影响

　 来源：120online    　 日期：2007-05-09

　　摘要　采用2.45GHz连续微波对大白兔进行全身大剂量急性辐照，对辐照前和辐照后的血液粘度、粘弹性、血小板聚集性、红细胞脆性、红细胞聚集性和变形性、骨压缩力学特性、骨弯曲力学特性等进行了对比实验，实验结果表明：微波辐照后血液的粘度和粘弹性值降低，红细胞聚集性和变形性降低，红细胞脆性增大，血小板聚集功能降低，2相聚集的解聚率增大，骨力学特性无显著变化。

Effects of Microwave Acute Irradiation on Biomechanic

　　Properties of Rabbit Tissues

　　Chen Hao　Li Xiaoyun　Zhang Fuxing　Yu Xiuyun　Liao Xiaoli

　　University of Electronic Science and Technology,Chengdu　610054

　　Abstract　The rabbit body was irradiated acutely by 2.45GHz continuous microwave. After irradiation, the values of blood viscosity, blood viscoelasticity, platelet aggregation,erythrocyte fragility, erythrocyte deformation, erythrocyte aggregation, the compressive mechanic property and flexible property of bones were tested. The data of irradiated group and unirradiated group were compared. The results showed:after microwave irradiation, the rabbit blood viscosity and viscoelasticity decreased; the rabbit platelet aggregation rate decreased and the disaggregation rate increased; the erythrocyte fragility increased; the biomechanic properties of bones did not change considerably.

　　Key words　Microwave　　Blood　　Bone　　Biomechanic property

　　1　概　述

　　2　材料与方法

　　2.1　材料

　　实验动物：新西兰大白兔40只，由华西医科大学动物房提供，体重(2.44±0.21) kg，不分雌雄，随机分为对照组和辐照组各20只。辐射系统：由磁控管、辐射腔和控制电路等组成，微波频率2.45 GHz，连续波，功率输出10～800 W，连续可调，功率大小按国家QB1198-91标准标定，输出时间控制在秒级。测试仪器：Low Shear 30流变仪(瑞士Contraves公司)，智能血液凝集仪(TYXN-91，上海)，721分光光度计(上海)，多功能力学实验台等。

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