Study and Application on the Device of the Drop Volume of
Amniotic Fluid in Estimating Fetal Lung Maturity
Liu Honglian Wang Weiguo Su Chengchang
Department of Physics, West China University of Medical Sciences, Chengdu 610041
Centre of Computer, West China University of Medical Sciences, Chengdu 610041
Abstract A novel device of drop volume of amniotic fluid has been made to estimate fetal lung maturity. The design of the device is based on the principle that the surface tension of amniotic fluid is inversely proportional to the quantity of surfactant in the solution. The device measures the falling time of fluid drops from drop-tube and estimates the fetal lung maturity by using the method of comparison and electric-optic timing-counting. 148 samples of amniotic fluid were measured by the device and the data were compared with those obtained by biochemical method. The results demonstrate that this device has high stability and accuracy, and the rate of agreement between the two methods is as high as 93%.
Key words Method of drop volume Surfactant Amniotic fluid Fetal lung maturity
由于胎儿肺内液体与羊水相通，故羊水的成分可反映肺内液体的成分。在临床医学上广泛应用并一致公认的是用生物化学法测定羊水中表面活性物质卵磷脂与鞘磷脂的比值(L/S)来确定胎儿肺成熟度。但是，此项实验检测既繁琐又费时，普通基层医院不具备此项检测条件。然而，采用作者研制的羊水滴量仪则可简便、快捷、经济、准确地检测出胎儿的肺成熟度。
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