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热解碳人工心脏瓣膜材料表面改性研究

  来源:120online      日期:2007-05-09
生物医学工程学杂志1999年第2期第16卷论著作者:黄 楠 杨 萍 冷永祥 程 璇单位:西南交通大学材料工程系,成都 610031关键词:人工心脏瓣膜材料;LTIC;表面改性;离子束;血液相容性...

  摘要 对氮离子注入热解碳及在热解碳表面离子束增强沉积钛氧化物薄膜进行了研究,采用X光电子能谱仪,俄歇电子能谱仪测定了表面改性层的成份和价态,用四探针方法测定了表面电阻率,用接触角方法测定了材料表面能,用动态凝血时间及血小板粘附评价了表面改性层的血液相容性。研究表明,热解碳经表面N+离子注入后有碳氮化合物形成,其血液相容性有所改善,而采用离子束增强沉积合成TiO2-x薄膜则使热解碳血液相容性获得了显著改善。

Surface Modification of Low Temperature Isotropic Pyrolytic

  Carbon Artificial Heart Valve Material

  Huang Nan Yang Ping Leng Yongxiang

  Department of Matebial Engineering, Southwest Jiaotong University, Chengdu 610031

  Abstract In this study, nitrogen ion implantation and titanium oxide film synthesized by ion beam enhanced deposition were adopted to treat low temperature isotropic pyrolytic carbon(LTIC).The chemical composition and valence state of the modified layer were determined by X-ray photoelectron spectroscopy (XPS) and Auger eletron spectroscopy (AES).The electric resisitance and the surface energy were measured by the four-probe system and the contact angle method respectively. The blood compatibility of the modified LTIC was evaluated by clotting time measurement and platelet adhesion test. The results showed that carbon-nitride was formed on the LTIC surface after N+ ion implantation, which had come effect on the improvement of blood compatibility, and a significant improvement of blood compatibility of LTIC coated by TiO2-x film was verified.

  Key words Artificial heart valve material  LTIC  Surface modification  Ion beam  Blood compatibility

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