降钙素基因相关肽阳性神经纤维在鼠颞下颌关节中的分布

　 来源：120online    　 日期：2007-05-07

　　摘　要：目的　观察鼠颞下颌关节中降钙素基因相关肽阳性神经纤维的分布特征。方法　将鼠颞下颌关节取出，脱钙脱水后恒冷切片，以ABC法漂染后进行镜检及半定量分析。结果　除关节盘中心区外，颞下颌关节各部位的软组织均有丰富的降钙素基因相关肽阳性纤维，主要沿血管尤其是动脉周围分布，密度为：前部盘周附着和关节囊(454.6±72.8)mm²、后部(302.7±43.4)mm²、外侧(240.2±23.6)mm²、内侧(229.6±25.0)mm²、盘外周区(202.4±35.2)mm²。结论　降钙素基因相关肽阳性纤维广泛分布于颞下颌关节中，是感觉神经的一部分，其密度以关节前部盘周附着及关节囊中最高。

Distribution of calcitonin gene-related peptide-like immunoreactive fibres in the temporomandibular joint of rat

LIU Xianghui

　　（Department of Stomatology, the Eighty-first Hospital of PLA, Nangjing 210002, China）

　　SI Fangjie

　　ZHOU Shuxia, et al.

　　Abstract：Objective　To observe the distribution of calcitonin gene-related peptide-like immunoreactive (CGRP-LI) nerve fibres in rat's tempormandibular joint (TMJ).Methods　The avidin-biotin-peroxidase complex method and image analysis were employed to detect CGRP-LI nerve fibres in frozen sections of TMJs in eight rats. Results　CGRP-LI nerve fibres were plentifully distributed in TMJs except the central disc band and bone, mainly in the periphery of blood vessels, especially arteries. Density: anterior disc attachment and capsule, (454.6±72.8) mm²; posterior portion, (302.7±43.4)mm²; lateral portion, (240.2±23.6)mm²; medial portion, (229.6±25.0)mm²; and peripheral portion of disc, (202.4±35.2)mm².Conclusion　CGRP-LI nerve fibres were widely distributed in rat TMJ and were a part of trigeminal sensory nerve. Density was highest in anterior disc attachment and capsule.

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