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HLA-DR抗原β链的共同表位与类风湿关节炎相关性研究

  来源:120online      日期:2007-05-04
中华风湿病学杂志2000年第3期第4卷论著作者:刘巧红 滕云 沈凌汛单位:刘巧红(430022武汉,同济医科大学附属协和医院风湿科);滕云(同济医科大学医学遗传研究室(滕云);沈凌汛(430022武汉,同济医科大学附属协和医院风湿科)关键词:关节炎,类风湿;抗原决定簇;HLA-DR抗原;聚合酶链反应-序列特异性引物...

  RA的临床表现复杂多样,共同表位可作为疾病严重性和预后的参考指标,在RA患者发病早期,可根据共同表位的检测情况采取针对性治疗,以及时控制病情。当然HLA-II类基因在RA发病中的作用仅占33%,说明有共同表位以外的机制在RA发病中起作用,尚需进一步研究。

  参 考 文 献

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(收稿日期:1999-11-18)

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