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托卡朋治疗帕金森病运动功能波动的临床观察

  来源:120online      日期:2007-05-07
中华老年医学杂志1999年第2期第18卷临床研究作者:王新德 张文记 陈生弟 翁中芳 刘道宽 王坚单位:100730 卫生部北京医院帕金森病和锥体外系疾病诊疗中心(王新德、张文记);上海第二医科大学附属瑞金医院神经科(陈生弟、翁中芳);上海医科大学附属华山医院神经科(刘道宽、王坚)...

  3 Rinne UK. Problems associated with long-term levodopa treatment of Parkinson's disease. Acta Neurol Scand Suppl, 1983,95:19-26.

  4 Mourakian MM, Chase TN. Levodopa response fluctuation in Parkinson's disease. Clin Neuropharmacol, 1988,11:378-385.

  5 Fabbrini G, Moruadian MM, Juncoo JL, et al. Motor fluctuations in Parkinson's disease. central pathophysiological mechanism. Part I. Ann Neurol, 1988,24:366-371.

  6 Jorga KM, Dingemanse J, Fotteler B, et al. Effect of a novel COMT-inhibitor on L-Dopa pharmacokinetic when combined with different Madopar formulations. New Tr Clin Neuropharmacol, 1994,8:274.

  7 Rayput AH, Martin W, Saint-Hilaire MH. Tolcapone improves motor function in parkinsonian patients with the “wearing off” phenomenon: a double-blind, placebocontrol, multicenter trial. Neurology, 1997,49:1066-1071.

  8 Myllyla VV, Jackson M, Larsen JP, et al. Efficacy and safety of tolcapone in Levodopa-treated Parkinson's disease patients with “wearing off” phenomenon: a multicentre, double blind, randomized, placebo-controlled trial. Europ J Neurol, 1997,4:333-341.

  9 Kurth MC, Adlcr CH, Hilaire ST, et al. Tolcapone improve motor function and reduces levodopa requirement in patients with Parkinson's disease experiencing motor fluctuation: a multitcenter, double-blind, randomized, placebo-controlled trial. Neurology, 1997,48:81-87.

(收稿:1998-08-07)

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