【摘要】 目的 探讨晚发性维生素K依赖因子缺乏致婴儿颅内血肿的诊断及治疗。方法 1992年1月~1998年12月,外科手术方法治疗的32例并发颅内血肿之晚发性维生素K依赖因子缺乏症患儿,其中单纯血肿清除9例;血肿清除+置管引流13例;单纯钻孔置管引流10例。结果 32例均治愈。29例获得1~4年随访,其中23例无任何神经系统后遗症,3例偏瘫,2例智力发育落后,1例癫痫。结论 本病有手术指征的颅内血肿及时行外科手术(血肿清除或引流术)是降低本病病死率及致残率的重要手段。
Surgical treatment for intracranial hematoma caused by delayed vitamin K deficiency bleeding in infants
LIANG Ping, XIA Zuozhong,LI Yingliang, et al
(Dept. of Neurosurgery, Children's Hospital, Chongqing Medical University, Chongqing 400014,China)
【Abstract】 Objective To appraise the diagnosis and treatment of intracranial hematomas caused by delayed Vitamin K deficiency bleeding syndrome in infants.Methods Thirty-two cases of intracranial hematomas were admitted between Jan.1992 and Dec. 1998. The surgical procedure included: 1) evacuation of hematoma ( n=9), 2) evacuation and catheter drainage ( n=13) and 3) puncture and catheter drainage (n=10).Results All cases recovered. Twenty-nine cases were followed-up for 1-4 years, Of them ,23 cases had no nervous sequelae, 3 had hemiparalysis, 2 had mental retardation and one epilepsy.Conclusion Prompt evacuation of hematoma is important to decrease the mortality and disability rate of intracranial hematomas caused by delayed Vitamin K deficiency bleeding syndrome.
【Key words】 Hematoma, subdural; Vitamin K deficiency; Infants.