4.骨骺软骨内的淋巴管,在次级骨化中心出现之前,主要分布在生长板增殖带以上的软骨内,骺近中心部位较多。次级骨化中心出现后,淋巴管多分布于生长板的静止带和增殖带。胎儿中后期,生长板的生长化骨能力增强,加之次级骨化中心的形成,代谢旺盛,被称为“排液系统”的淋巴管具有较毛细血管更大的通透性,能够清除大分子代谢产物和坏死的细胞,辅助静脉回流,维持软骨组织正常的渗透压及结构平衡[2,11],保持骨骺软骨的生物力学特性。同时,新生儿骨骺生长板的血运屏障尚未建立,贯穿生长板的淋巴管有可能参与干骺端与骨骺之间的炎症、肿瘤的蔓延或扩散,在骨骺软骨疾病的演变过程中发挥作用。
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